Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach
KeywordAldo-keto reductase 1C3; AKR1C3; 17β-HSD5; Prostate cancer; CRPC; Bioisosterism; Scaffold hopping; Inhibitors
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