Preclinical evaluation of pharmacological strategies designed to enhance the activity of established and novel anti-cancer drugs. Synopsis: Evaluation of pharmacological strategies designed to modulate the Warburg effect, enhance the activity of tyrosine kinase inhibitors and novel analogues of Temozolomide.
AuthorSaleem, Mohammed Umer
SupervisorPhillips, Roger M.
KeywordWarburg effect; Glutamine metabolism; Tyrosine kinase inhibitors; Dichloroacetate; Pyruvate dehydrogenase kinase; Temozolomide; Chemosensitivity
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InstitutionUniversity of Bradford
DepartmentInstitute of Cancer Therapeutics