Design, Synthesis and Biological Evaluation of Inhibitors of Polysialyltransferases PST and STX. Design, synthesis and biological evaluation of a range of N-modified mannosamines, sialic acids and analogues from in silico screening as inhibitors of PolySia-NCAM biosynthesis with anti-migration activity.
dc.contributor.advisor | Falconer, Robert A. | |
dc.contributor.advisor | Patterson, Laurence H. | |
dc.contributor.author | Springett, Bradley R. | * |
dc.date.accessioned | 2017-10-24T15:57:40Z | |
dc.date.available | 2017-10-24T15:57:40Z | |
dc.date.issued | 2013 | |
dc.identifier.uri | http://hdl.handle.net/10454/13528 | |
dc.description.sponsorship | EPSRC and BACR | en_US |
dc.language.iso | en | en_US |
dc.rights | <a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/3.0/"><img alt="Creative Commons License" style="border-width:0" src="http://i.creativecommons.org/l/by-nc-nd/3.0/88x31.png" /></a><br />The University of Bradford theses are licenced under a <a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/3.0/">Creative Commons Licence</a>. | eng |
dc.subject | Polysialic acid; Neural cell adhesion molecule; Polysialyltransferases; Cancer; N-acyl modified sialic acid | en_US |
dc.title | Design, Synthesis and Biological Evaluation of Inhibitors of Polysialyltransferases PST and STX. Design, synthesis and biological evaluation of a range of N-modified mannosamines, sialic acids and analogues from in silico screening as inhibitors of PolySia-NCAM biosynthesis with anti-migration activity. | en_US |
dc.type.qualificationlevel | doctoral | en_US |
dc.publisher.institution | University of Bradford | eng |
dc.publisher.department | Institute of Cancer Therapeutics, School of Life Sciences | en_US |
dc.type | Thesis | eng |
dc.type.qualificationname | PhD | en_US |
dc.date.EndofEmbargo | 2024-02-02 | |
dc.date.awarded | 2013 | |
dc.description.publicnotes | The abstract and full text will be available at the end of an embargo period, 2nd Feb 2024. | en |
refterms.dateFOA | 2021-02-02T11:15:37Z |