Design, Synthesis and Biological Evaluation of Inhibitors of Polysialyltransferases PST and STX. Design, synthesis and biological evaluation of a range of N-modified mannosamines, sialic acids and analogues from in silico screening as inhibitors of PolySia-NCAM biosynthesis with anti-migration activity.

Springett, Bradley R.

dc.contributor.advisor	Falconer, Robert A.
dc.contributor.advisor	Patterson, Laurence H.
dc.contributor.author	Springett, Bradley R.	*
dc.date.accessioned	2017-10-24T15:57:40Z
dc.date.available	2017-10-24T15:57:40Z
dc.date.issued	2013
dc.identifier.uri	http://hdl.handle.net/10454/13528
dc.description.sponsorship	EPSRC and BACR	en_US
dc.language.iso	en	en_US
dc.rights	<a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/3.0/"><img alt="Creative Commons License" style="border-width:0" src="http://i.creativecommons.org/l/by-nc-nd/3.0/88x31.png" /></a><br />The University of Bradford theses are licenced under a <a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/3.0/">Creative Commons Licence</a>.	eng
dc.subject	Polysialic acid; Neural cell adhesion molecule; Polysialyltransferases; Cancer; N-acyl modified sialic acid	en_US
dc.title	Design, Synthesis and Biological Evaluation of Inhibitors of Polysialyltransferases PST and STX. Design, synthesis and biological evaluation of a range of N-modified mannosamines, sialic acids and analogues from in silico screening as inhibitors of PolySia-NCAM biosynthesis with anti-migration activity.	en_US
dc.type.qualificationlevel	doctoral	en_US
dc.publisher.institution	University of Bradford	eng
dc.publisher.department	Institute of Cancer Therapeutics, School of Life Sciences	en_US
dc.type	Thesis	eng
dc.type.qualificationname	PhD	en_US
dc.date.EndofEmbargo	2024-02-02
dc.date.awarded	2013
dc.description.publicnotes	The abstract and full text will be available at the end of an embargo period, 2nd Feb 2024.	en
refterms.dateFOA	2021-02-02T11:15:37Z