Design, Synthesis and Biological Evaluation of Inhibitors of Polysialyltransferases PST and STX. Design, synthesis and biological evaluation of a range of N-modified mannosamines, sialic acids and analogues from in silico screening as inhibitors of PolySia-NCAM biosynthesis with anti-migration activity.
End of Embargo2021-01-18
AuthorSpringett, Bradley R.
SupervisorFalconer, Robert A.
Patterson, Laurence H.
KeywordPolysialic acid; Neural cell adhesion molecule; Polysialyltransferases; Cancer; N-acyl modified sialic acid
The University of Bradford theses are licenced under a Creative Commons Licence.
InstitutionUniversity of Bradford
DepartmentInstitute of Cancer Therapeutics, School of Life Sciences