Mechanistic approaches towards understanding particle formation in biopharmaceutical formations. The role of sufactant type and level on protein conformational stability, as assessed by calorimetry, and on protein size stability as assessed by dynamic light scattering, micro flow imaging and HIAC
SupervisorForbes, Robert T.
KeywordSurfactant; High Sensitivity Differential Scanning Calorimetry (HSDSC); Liquid Particle Counter (HIAC); Micro-flow Imaging (MFI); Aggregation; Protein stabilization; Protein conformational stability, Sub-visible particles; Antibody IgG2; Bovine serum albumin (BSA); Size distribution
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InstitutionUniversity of Bradford
DepartmentFaculty of Life Sciences