Co-processing of drugs and co-crystal formers and its effect on pharmaceutical dosage-form performance. Co-crystallization of urea/ 2-methoxybenzamide, caffeine/ malonic acid, caffeine/ oxalic acid and theophylline/ malonic acid systems: Solid-state characterization including imaging, thermal, X-ray and Raman spectroscopic techniques with subsequent evaluation of tableting behaviour
AuthorIbrahim Mohamed, Asim Y.
SupervisorForbes, Robert T.
Grimsey, Ian M.
Bonner, Michael C.
KeywordCo-crystals; Co-crystallization; Urea; 2-methoxybenzamide; Caffeine; Malonic acid; Oxalic acid; Theophylline; Pharmaceutical dosage-form performance; Convection mixing; Compaction; Tensile strength
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InstitutionUniversity of Bradford
DepartmentDrug Delivery Group, School of Pharmacy