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dc.contributor.authorKatsikogianni, Maria G.*
dc.contributor.authorWood, David J.*
dc.contributor.authorMissirlis, Y.F.*
dc.date.accessioned2017-03-07T14:29:34Z
dc.date.available2017-03-07T14:29:34Z
dc.date.issued2016
dc.identifier.citationKatsikogianni MG, Wood DJ and Missirlis YF (2016) Biomaterial functionalized surfaces for reducing bacterial adhesion and infection. In: Handbook of Bioceramics and Biocomposites. Springer. pp 1-28.
dc.identifier.urihttp://hdl.handle.net/10454/11554
dc.descriptionNo
dc.description.abstractThis chapter describes the current approaches to reduce bacterial adhesion to various biomaterial surfaces, focusing on nonfouling surfaces through patterning and hydrophobicity plasma-assisted surface treatment and deposition; incorporation of antimicrobials, antibiotics, antibiofilms, and natural extracts that are either immobilized or released; dual function antimicrobial surfaces; incorporation of nonpathogenic bacteria, bacteriophages, and biofilm dispersal agents but also reduced bacterial adhesion through tissue integration. To facilitate the design of new materials, the role of physical, chemical, and biological surface properties on bacterial adhesion is reviewed in each case, as an insight into the chemical and physical cues that affect bacterial adhesion and biofilm formation can provide ideas for creating successful antifouling or antimicrobial surfaces. The application of these surfaces is explored based on the clinical needs and the market gaps. How multidisciplinary research on surface design and engineering may have an impact on both fundamental understanding of bacterial adhesion to biomaterials and applied biomaterial science and technology is finally discussed.
dc.language.isoen
dc.subjectBacterial adhesion
dc.subjectBiomaterials
dc.subjectSurface chemistry
dc.subjectSurface energy
dc.subjectSurface charge
dc.subjectSurface topography
dc.subjectSelf-assembly
dc.subjectPlasma treatment
dc.subjectPlasma deposition
dc.subjectAntifouling
dc.subjectAntimicrobials
dc.subjectAntibiotics
dc.subjectNatural extracts
dc.subjectSurface analysis
dc.subjectAdhesion mechanism
dc.subjectFluid shear
dc.titleBiomaterial Functionalized Surfaces for Reducing Bacterial Adhesion and Infection
dc.status.refereedYes
dc.typeBook chapter
dc.type.versionNo full-text in the repository
dc.identifier.doihttps://doi.org/10.1007/978-3-319-09230-0_32-1
dc.openaccess.statusclosedAccess


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