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dc.contributor.authorKatsikogianni, Maria G.*
dc.contributor.authorHancock, R.E.W.*
dc.contributor.authorDevine, D.A.*
dc.contributor.authorWood, David J.*
dc.date.accessioned2017-03-02T15:59:20Z
dc.date.available2017-03-02T15:59:20Z
dc.date.issued2015
dc.identifier.citationKatsikogianni MG, Hancock REW, Devine DA and Wood DJ (2015) Cell vs. bacterial viability in the presence of host defence peptides and RGD. eCells & Materials Supplement. 30(2): 55.en_US
dc.identifier.urihttp://hdl.handle.net/10454/11521
dc.descriptionyesen_US
dc.description.abstractMore than 2 million people/year suffer a bone fracture in the UK1. Reconstruction of bone defects represents a major clinical challenge and is addressed using a number of medical devices. Although medical device compositions and applications may differ widely, all attract microorganisms and represent niches for medical device associated infections. For open fractures, the risk of infection can be 55%2. These infections are often resistant to many of the currently available antibiotics and represent a huge and growing financial and healthcare burden. The aim of this study was a fundamental understanding of how the presence of host defence peptides (HDPs)3 and/or RGD can influence the outcome of cell vs. bacterial viability and proliferation.en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttp://www.ecmjournal.org/journal/supplements/vol030supp02/pdf/Vol030Supp02a055.pdfen_US
dc.rights© 2015 The Authors. Published by AO Research Insititute Davos. Reproduced in accordance with the publisher's self-archiving policy.en_US
dc.subjectHuman bone; Fractures; Bacterial viability; Antibiotics; Host defence peptides (HDPs)3; RGDen_US
dc.titleCell vs. bacterial viability in the presence of host defence peptides and RGDen_US
dc.status.refereedyesen_US
dc.typeConference paperen_US
dc.type.versionPublished versionen_US
dc.description.publicnotesPresented at the conference: eCM XVI - Bone and Implant Infection June 24-26, 2015, Convention Centre, Davos Platz, Switzerland.en_US
refterms.dateFOA2018-07-25T15:31:35Z


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