Show simple item record

dc.contributor.authorKatsikogianni, Maria*
dc.contributor.authorHancock, R.E.W.*
dc.contributor.authorDevine, D.A.*
dc.contributor.authorWood, David J.*
dc.date.accessioned2017-03-02T15:59:20Z
dc.date.available2017-03-02T15:59:20Z
dc.date.issued2015
dc.identifier.citationKatsikogianni MG, Hancock REW, Devine DA and Wood DJ (2015) Cell vs. bacterial viability in the presence of host defence peptides and RGD. eCells & Materials Supplement. 30(2): 55.
dc.identifier.urihttp://hdl.handle.net/10454/11521
dc.descriptionYes
dc.description.abstractMore than 2 million people/year suffer a bone fracture in the UK1. Reconstruction of bone defects represents a major clinical challenge and is addressed using a number of medical devices. Although medical device compositions and applications may differ widely, all attract microorganisms and represent niches for medical device associated infections. For open fractures, the risk of infection can be 55%2. These infections are often resistant to many of the currently available antibiotics and represent a huge and growing financial and healthcare burden. The aim of this study was a fundamental understanding of how the presence of host defence peptides (HDPs)3 and/or RGD can influence the outcome of cell vs. bacterial viability and proliferation.
dc.language.isoen
dc.rights© 2015 The Authors. Published by AO Research Insititute Davos. Reproduced in accordance with the publisher's self-archiving policy.
dc.subjectHuman bone
dc.subjectFractures
dc.subjectBacterial viability
dc.subjectAntibiotics
dc.subjectHost defence peptides (HDPs)3
dc.subjectRGD
dc.titleCell vs. bacterial viability in the presence of host defence peptides and RGD
dc.status.refereedYes
dc.typeConference paper
dc.type.versionPublished version
dc.description.publicnotesPresented at the conference: eCM XVI - Bone and Implant Infection June 24-26, 2015, Convention Centre, Davos Platz, Switzerland.
dc.rights.licenseUnspecified
refterms.dateFOA2018-07-25T15:31:35Z
dc.relation.urlhttp://www.ecmjournal.org/journal/supplements/vol030supp02/pdf/Vol030Supp02a055.pdf
dc.openaccess.statusopenAccess


Item file(s)

Thumbnail
Name:
eCM_Katsikogianni_2015.pdf
Size:
139.9Kb
Format:
PDF
Description:
Main article

This item appears in the following Collection(s)

Show simple item record