Core (Polystyrene)−Shell [Poly(glycerol monomethacrylate)] Particles
dc.contributor.author | Mckenzie, A. | * |
dc.contributor.author | Hoskins, Richard | * |
dc.contributor.author | Swift, Thomas | * |
dc.contributor.author | Grant, Colin A. | * |
dc.contributor.author | Rimmer, Stephen | * |
dc.date.accessioned | 2017-02-27T14:08:54Z | |
dc.date.available | 2017-02-27T14:08:54Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Mckenzie A, Hoskins R, Swift T et al (2017) Core (Polystyrene)−Shell [Poly(glycerol monomethacrylate)] Particles. ACS Applied Materials and Interfaces. 9(8): 7577-7590. | en_US |
dc.identifier.uri | http://hdl.handle.net/10454/11485 | |
dc.description | Yes | en_US |
dc.description.abstract | A set of water-swollen core−shell particles was synthesized by emulsion polymerization of a 1,3-dioxolane functional monomer in water. After removal of the 1,3- dioxolane group, the particles’ shells were shown to swell in aqueous media. Upon hydrolysis, the particles increased in size from around 70 to 100−130 nm. A bicinchoninic acid assay and ζ-potential measurements were used to investigate the adsorption of lysozyme, albumin, or fibrinogen. Each of the core−shell particles adsorbed significantly less protein than the noncoated core (polystyrene) particles. Differences were observed as both the amount of difunctional, cross-linking monomer and the amount of shell monomer in the feed were changed. The core−shell particles were shown to be resistant to protein adsorption, and the degree to which the three proteins adsorbed was dependent on the formulation of the shell. | en_US |
dc.description.sponsorship | EPSRC and MRC | en_US |
dc.language.iso | en | en_US |
dc.rights | (c) 2017 ACS. This is an Open Access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html), which permits copying and redistribution of the article or any adaptations for non-commercial purposes. | en_US |
dc.subject | Core-shell; Particles; Emulsion polymerisation; Hydrogel; Protein adsorption | en_US |
dc.title | Core (Polystyrene)−Shell [Poly(glycerol monomethacrylate)] Particles | en_US |
dc.status.refereed | Yes | en_US |
dc.date.Accepted | 2017-02-13 | |
dc.date.application | 2017-02-13 | |
dc.type | Article | en_US |
dc.type.version | Published version | en_US |
dc.identifier.doi | https://doi.org/10.1021/acsami.6b15004 | |
refterms.dateFOA | 2018-07-25T16:03:02Z |