Show simple item record

dc.contributor.authorPinnock, A.*
dc.contributor.authorShivshetty, N.*
dc.contributor.authorRoy, S.*
dc.contributor.authorRimmer, Stephen*
dc.contributor.authorDouglas, I.*
dc.contributor.authorMacNeil, S.*
dc.contributor.authorGary, P.*
dc.date.accessioned2017-02-15T15:13:46Z
dc.date.available2017-02-15T15:13:46Z
dc.date.issued2017
dc.identifier.citationPinnock A, Shivshetty N, Roy S et al (2017) Ex vivo rabbit and human corneas as models for bacterial and fungal keratitis. Graeve’s Archive for Clinical and Experimental Ophthalmology. 255(2): 333-342.en_US
dc.identifier.urihttp://hdl.handle.net/10454/11370
dc.descriptionYesen_US
dc.description.abstractIn the study of microbial keratitis, in vivo animal models often require a large number of animals, and in vitro monolayer cell culture does not maintain the three-dimensional structure of the tissues or cell-to-cell communication of in vivo models. Here, we propose reproducible ex vivo models of single- and dual-infection keratitis as an alternative to in vivo and in vitro models.en_US
dc.description.sponsorshipWellcome Trusten_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttp://dx.doi.org/10.1007/s00417-016-3546-0en_US
dc.rights© 2017 The Authors. This is an Open Access article distributed under the Creative Commons CC-BY license (http://creativecommons.org/licenses/by/4.0/)en_US
dc.subjectEx vivo cornea; Microbial keratitis; Colony-forming units; Corneal modelen_US
dc.titleEx vivo rabbit and human corneas as models for bacterial and fungal keratitisen_US
dc.status.refereedYesen_US
dc.date.Accepted2016-10-31
dc.date.application2016-11-14
dc.typeArticleen_US
dc.type.versionPublished versionen_US
refterms.dateFOA2018-07-25T16:03:54Z


Item file(s)

Thumbnail
Name:
pinnock_et_al_2017.pdf
Size:
2.820Mb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record