Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances
dc.contributor.author | Pitto-Barry, Anaïs | * |
dc.contributor.author | Barry, Nicolas P.E. | * |
dc.date.accessioned | 2017-01-31T10:44:26Z | |
dc.date.available | 2017-01-31T10:44:26Z | |
dc.date.issued | 2014-05 | |
dc.identifier.citation | Pitto-Barry A and Barry NPE (2014) Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances. Polymer Chemistry. 5(10): 3291-3297. | en_US |
dc.identifier.uri | http://hdl.handle.net/10454/11223 | |
dc.description | Yes | en_US |
dc.description.abstract | This mini-review highlights the latest advances in the chemistry and biology of Pluronic® triblock copolymers. We focus on their applications in medicine, as drug delivery carriers, biological response modifiers, and pharmaceutical ingredients. Examples of drug delivery systems and formulations currently in clinical use, clinical trials or preclinical development are highlighted. We also discuss the role that Pluronic® copolymers may play in the innovative design of new nanomedicines in the near future. | en_US |
dc.description.sponsorship | We thank the Leverhulme Trust (Early Career Fellowship no. ECF-2013-414 to NPEB), the University of Warwick (Grant no. RDF 2013-14 to NPEB) and EPSRC (EP/G004897/1 to APB) for support. | en_US |
dc.language.iso | en | en_US |
dc.rights | © 2014 The Royal Society of Chemistry. Reproduced in accordance with the publisher's self-archiving policy. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. | en_US |
dc.subject | Pluronic® triblock copolymers; Medicine; Drug delivery carriers; Biological response modifiers; Pharmaceutical ingredients; Clinical advances | en_US |
dc.title | Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances | en_US |
dc.status.refereed | Yes | en_US |
dc.date.Accepted | 2014-02-11 | |
dc.date.application | 2014-03-24 | |
dc.type | Article | en_US |
dc.type.version | Published version | en_US |
dc.identifier.doi | https://doi.org/10.1039/C4PY00039K | |
refterms.dateFOA | 2018-07-26T09:40:49Z |