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    Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

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    Publication date
    2014-05
    Author
    Pitto-Barry, Anaïs
    Barry, Nicolas P.E.
    Keyword
    Pluronic® triblock copolymers; Medicine; Drug delivery carriers; Biological response modifiers; Pharmaceutical ingredients; Clinical advances
    Rights
    © 2014 The Royal Society of Chemistry. Reproduced in accordance with the publisher's self-archiving policy. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
    Peer-Reviewed
    Yes
    
    Metadata
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    Abstract
    This mini-review highlights the latest advances in the chemistry and biology of Pluronic® triblock copolymers. We focus on their applications in medicine, as drug delivery carriers, biological response modifiers, and pharmaceutical ingredients. Examples of drug delivery systems and formulations currently in clinical use, clinical trials or preclinical development are highlighted. We also discuss the role that Pluronic® copolymers may play in the innovative design of new nanomedicines in the near future.
    URI
    http://hdl.handle.net/10454/11223
    Version
    Published version
    Citation
    Pitto-Barry A and Barry NPE (2014) Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances. Polymer Chemistry. 5(10): 3291-3297.
    Link to publisher’s version
    http://dx.doi.org/10.1039/C4PY00039K
    Type
    Article
    Collections
    Life Sciences Publications

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