Increasing elastin fibre production in a tissue engineered mesh for pelvic floor surgery
dc.contributor.author | Osman, N. | * |
dc.contributor.author | Roman, S. | * |
dc.contributor.author | Sefat, Farshid | * |
dc.contributor.author | Bullock, A.J. | * |
dc.contributor.author | Chapple, C.R. | * |
dc.date.accessioned | 2017-01-20T15:33:26Z | |
dc.date.available | 2017-01-20T15:33:26Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Osman I, Roman S, Sefat F, Bullock AJ and Chapple CR (2014) Increasing elastin fibre production in a tissue engineered mesh for pelvic floor surgery. European Urology Supplements. 13(1): 483. | en_US |
dc.identifier.uri | http://hdl.handle.net/10454/11154 | |
dc.description | yes | en_US |
dc.description.abstract | Polypropylene mesh for pelvic floor surgery is associated with serious complications ( e.g. erosion). A biodegradable tissue engineered mesh composed of a polylactic acid (PLA) scaffold seeded with autologous cells is a promising alternative. However, thus far elastin content (important for elastic recoil) in this tissue has been low. We aimed to increase elastin expression and test the resultant tensile properties. | en_US |
dc.language.iso | en | en_US |
dc.rights | © 2014 Elsevier. Reproduced in accordance with the publisher's self-archiving policy. This manuscript version is made available under the CC-BY-NC-ND 4.0 license. | en_US |
dc.subject | Pelvic floor; Mesh; Elastin fibre; Biodegradable; Tissue engineering | en_US |
dc.title | Increasing elastin fibre production in a tissue engineered mesh for pelvic floor surgery | en_US |
dc.status.refereed | yes | en_US |
dc.type | Article | en_US |
dc.type.version | Accepted Manuscript | en_US |
dc.identifier.doi | https://doi.org/10.1016/S1569-9056(14)60476-0 | |
refterms.dateFOA | 2018-07-26T09:41:43Z |