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    Effect of transforming growth factor-β on up/down regulation of integrin-β1 in primary chondrocyte culture

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    Publication date
    2016
    Author
    Khaghani, Seyed A.
    Sefat, Farshid
    Youseffi, Mansour
    Rehman, R.
    Soon, Chin Fhong
    Akbarova, G.
    Keyword
    Growth factor-β; Integrin-β1; Regulation; Primary chondrocyte culture; Cell adhesion molecules (CAMs); Tissue engineering
    Rights
    © 2016 The Authors. Published by eCM. With kind permission of full reproduction from eCM journal (www.ecmjournal.org). Founded by scientists for the benefit of Science rather than profit. DOI: http://dx.doi.org/10.3791/51826.
    Peer-Reviewed
    yes
    
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    Abstract
    Regeneration of a damaged or non-functioning tissue requires adhesion of cells to their extracellular matrix (ECM). Thus the investigation of the level of synthesised cell adhesion molecules (CAMs) in cell culture systems play major roles in cell and tissue engineering. Adhesion of chondrocyte to a collagen type-II rich matrix, is dependent on cell adhesion molecules (CAMs) and integrins and cells adhere to ECM through integrins.
    URI
    http://hdl.handle.net/10454/11153
    Version
    Published version
    Citation
    Khaghani SA, Sefat F, Youseffi M, Rehman R, Soon CF and Akbarova G (2016) Effect of transforming growth factor-β on up/down regulation of integrin-β1 in primary chondrocyte culture. European Cells and Materials, August 2016, UCL, London, UK. In: European Cells and Materials, Vol 32, Suppl 4, p 56.
    Link to publisher’s version
    http://www.ecmjournal.org/index.htm
    Type
    Article
    Collections
    Engineering and Digital Technology Publications

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