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dc.contributor.authorSwift, Thomas*
dc.contributor.authorLapworth, J.*
dc.contributor.authorSwindells, K.*
dc.contributor.authorSwanson, L.*
dc.contributor.authorRimmer, Stephen*
dc.date.accessioned2016-12-22T14:31:29Z
dc.date.available2016-12-22T14:31:29Z
dc.date.issued2016
dc.identifier.citationSwift T, Lapworth J, Swindells K et al (2016) pH responsive highly branched poly(N-isopropylacrylamide) with trihistidine or acid chain ends. RSC Advances. 75: 71345-71350.en_US
dc.identifier.urihttp://hdl.handle.net/10454/11041
dc.descriptionYesen_US
dc.description.abstractThermally responsive highly branched poly(N-isopropyl acrylamide)s (HB-PNIPAM) were prepared and end-functionalised to give polymers with acid or trihistidine end groups. These polymers exhibit a broad coil-to-globule transition across a wide temperature range which can be measured using covalently attached fluorescent tags. The acid chain ends provided a material with a distinct change in solution behaviour at pH close to the pKa of the carboxylate group. At pH 11 this polymer did not show a cloud point up to 50 °C but fluorescence measurements on the labelled polymers showed that a coil to glubule transition did take place. The globular state, above the LCST, appeared to be more swollen if the end group carried charge then when it was uncharged. A polymer with trihistidine and free carboxylate chain ends, which contained multiple charges at various pH, did show LCSTs at all pH and the polymer globule was shown to be swollen at each pH.en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttp://dx.doi.org/10.1039/C6RA13139Een_US
dc.subjectPolymers; Trihistidine; Carboxylate chain ends; Acid chain ends; Thermal responsivenessen_US
dc.titlepH Responsive Highly Branched Poly(N-isopropylacrylamide) with Trihistidine or Acid Chain Endsen_US
dc.status.refereedYesen_US
dc.date.Accepted2016-07-06
dc.date.application2016-07-19
dc.typeArticleen_US
dc.type.versionAccepted Manuscripten_US
refterms.dateFOA2018-07-25T15:53:05Z


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