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    Resistance of degraded hair shafts to contaminant DNA

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    Publication date
    2006-01-27
    Author
    Gilbert, M.T.P.
    Menez, L.
    Janaway, Robert C.
    Tobin, Desmond J.
    Cooper, A.
    Wilson, Andrew S.
    Keyword
    Hair; Degradation; Human remains; DNA; Contamination
    Peer-Reviewed
    Yes
    
    Metadata
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    Abstract
    We have investigated the susceptibility of degraded human hair shaft samples to contamination by exogenous sources of DNA, including blood, saliva, skin cells, and purified DNA. The results indicate that on the whole hair shafts are either largely resistant to penetration by contaminant DNA, or extremely easy to successfully decontaminate. This pertains to samples that are both morphologically and biochemically degraded. We suggest that this resistance to the incorporation of contaminant DNA relates to the hydrophobic and impermeable nature of the keratin structures forming the hair shaft. Therefore, hair samples represent an important and underestimated source of DNA in both forensic and ancient DNA studies.
    URI
    http://hdl.handle.net/10454/10948
    Version
    No full-text in the repository
    Citation
    Gilbert MT, Menez L, Janaway RC et al (2006) Resistance of degraded hair shafts to contaminant DNA. Forensic Science International. 156(2-3): 208-212.
    Link to publisher’s version
    http://dx.doi.org/10.1016/j.forsciint.2005.02.021
    Type
    Article
    Collections
    Life Sciences Publications

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