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    Anti-ulcer xanthones from the roots of Hypericum oblongifolium Wall

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    Publication date
    2014
    Author
    Ali, M.
    Latif, A.
    Zaman, K.
    Arfan, M.
    Maitland, Derek J.
    Ahmad, H.
    Ahmad, M.
    Keyword
    Hypericum oblongifolium wall; Xanthones; Hypericorin C; Hypericorin D; 2D-NMR; Anti-ulcer
    Peer-Reviewed
    Yes
    
    Metadata
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    Abstract
    Three new xanthones, hypericorin C (1), hypericorin D (2) and 3,4-dihydroxy-5-methoxyxanthone (3), along with eight known compounds; 2,3-dimethoxyxanthone (4), 3,4-dihydroxy-2-methoxyxanthone (5), 3,5-dihydroxy-1-methoxyxanthone (6), 3-acetylbetulinic acid (7), 10H-1,3-dioxolo[4,5-b]xanthen-10-one (8), 3-hydroxy-2-methoxyxanthone (9), 3,4,5-trihydroxyxanthone (10) and betulinic acid (11) were isolated from the roots of Hypericum oblongifolium. The structures of the new compounds 1, 2 and 3 were deduced by spectroscopic techniques [ESI MS, (1)H NMR, (13)C NMR, and 2D NMR (HMQC, HMBC, COSY and NOESY)]. The entire series of compounds were evaluated for anti-ulcer activity.
    URI
    http://hdl.handle.net/10454/10415
    Version
    No full-text available in the repository
    Citation
    Ali M, Latif A, Zaman K et al (2014) Anti-ulcer xanthones from the roots of Hypericum oblongifolium Wall. Fitoterapia. 95: 258-265.
    Link to publisher’s version
    https://doi.org/10.1016/j.fitote.2014.03.014
    Type
    Article
    Collections
    Life Sciences Publications

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