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dc.contributor.authorDickerson, J.*
dc.contributor.authorBird, P.K.*
dc.contributor.authorMcEachan, R.R.C.*
dc.contributor.authorPickett, K.E.*
dc.contributor.authorWaiblinger, D.*
dc.contributor.authorUphoff, E.P.*
dc.contributor.authorMason, Dan*
dc.contributor.authorBryant, M.*
dc.contributor.authorBywater, T.*
dc.contributor.authorBowyer-Crane, C.*
dc.contributor.authorSahota, P.*
dc.contributor.authorSmall, Neil A.*
dc.contributor.authorHowell, M.*
dc.contributor.authorThornton, G.*
dc.contributor.authorAstin, M.*
dc.contributor.authorLawlor, D.A.*
dc.contributor.authorWright, J.*
dc.date.accessioned2016-10-25T14:32:56Z
dc.date.available2016-10-25T14:32:56Z
dc.date.issued2016-08-04
dc.identifier.citationDickerson J, Bird PK, McEachan RRC et al (2016) Born in Bradford’s Better Start: an experimental birth cohort study to evaluate the impact of early life interventions. BMC Public Health. 16: 711.en_US
dc.identifier.urihttp://hdl.handle.net/10454/10066
dc.descriptionYesen_US
dc.description.abstractBackground: Early interventions are recognised as key to improving life chances for children and reducing inequalities in health and well-being, however there is a paucity of high quality research into the effectiveness of interventions to address childhood health and development outcomes. Planning and implementing standalone RCTs for multiple, individual interventions would be slow, cumbersome and expensive. This paper describes the protocol for an innovative experimental birth cohort: Born in Bradford’s Better Start (BiBBS) that will simultaneously evaluate the impact of multiple early life interventions using efficient study designs. Better Start Bradford (BSB) has been allocated £49 million from the Big Lottery Fund to implement 22 interventions to improve outcomes for children aged 0–3 in three key areas: social and emotional development; communication and language development; and nutrition and obesity. The interventions will be implemented in three deprived and ethnically diverse inner city areas of Bradford. Method: The BiBBS study aims to recruit 5000 babies, their mothers and their mothers’ partners over 5 years from January 2016-December 2020. Demographic and socioeconomic information, physical and mental health, lifestyle factors and biological samples will be collected during pregnancy. Parents and children will be linked to their routine health and local authority (including education) data throughout the children’s lives. Their participation in BSB interventions will also be tracked. BiBBS will test interventions using the Trials within Cohorts (TwiCs) approach and other quasi-experimental designs where TwiCs are neither feasible nor ethical, to evaluate these early life interventions. The effects of single interventions, and the cumulative effects of stacked (multiple) interventions on health and social outcomes during the critical early years will be measured. Discussion: The focus of the BiBBS cohort is on intervention impact rather than observation. As far as we are aware BiBBS is the world’s first such experimental birth cohort study. While some risk factors for adverse health and social outcomes are increasingly well described, the solutions to tackling them remain elusive. The novel design of BiBBS can contribute much needed evidence to inform policy makers and practitioners about effective approaches to improve health and well-being for future generations.en_US
dc.description.sponsorshipBig Lotteryen_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttp://dx.doi.org/10.1186/s12889-016-3318-0en_US
dc.rights© 2016 The Author(s). Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en_US
dc.subjectBig cohort; Trials within cohort; Quasi-experimental; Inequalities; Early years interventions; Child healthen_US
dc.titleBorn in Bradford's Better Start: an experimental birth cohort study to evaluate the impact of early life interventionsen_US
dc.status.refereedYesen_US
dc.date.Accepted2016-07-08
dc.typeArticleen_US
dc.type.versionpublished version paperen_US
refterms.dateFOA2018-07-27T01:58:50Z


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