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Nanoparticles for post-infarct ventricular remodeling
Dong, C. Ma, A. Shang, Lijun
Dong, C.
Ma, A.
Shang, Lijun
Publication Date
2018-12
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© 2018 Caijuan Dong . Reproduced in accordance with the publisher's self-archiving policy.
Peer-Reviewed
Yes
Open Access status
i
Accepted for publication
2018-10-05
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Abstract
In recent years, tremendous progress has been made in the treatment of acute myocardial infarction (AMI), but pathological ventricular remodeling often causes survivors to suffer from fatal heart failure. Currently, there is no effective therapy to attenuate ventricular remodeling. Recently, nanoparticles-based drug delivery system is widely applied in biomedicine especially in cancer and liver fibrosis, owing to its excellent physical, chemical, and biological properties. Therefore, using nanoparticles as delivery vehicles of small molecules, polypeptides, etc to improve post-infarct ventricular remodeling are expected. In this review, we summarized the updated researches in this fast-growing area and suggested further works needed.
Version
Accepted manuscript
Citation
Dong C, Ma A and Shang L (2018) Nanoparticles for post-infarct ventricular remodeling. Nanomedicine. 13(23): 3037-3050.
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Article