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Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances
Pitto-Barry, Anaïs Barry, Nicolas P.E.
Pitto-Barry, Anaïs
Barry, Nicolas P.E.
Publication Date
2014-05
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© 2014 The Royal Society of Chemistry. Reproduced in accordance with
the publisher's self-archiving policy. This article is licensed under a Creative Commons
Attribution 3.0 Unported Licence.
Peer-Reviewed
Yes
Open Access status
openAccess
Accepted for publication
2014-02-11
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Abstract
This mini-review highlights the latest advances in the chemistry and biology of Pluronic® triblock copolymers. We focus on their applications in medicine, as drug delivery carriers, biological response modifiers, and pharmaceutical ingredients. Examples of drug delivery systems and formulations currently in clinical use, clinical trials or preclinical development are highlighted. We also discuss the role that Pluronic® copolymers may play in the innovative design of new nanomedicines in the near future.
Version
Published version
Citation
Pitto-Barry A and Barry NPE (2014) Pluronic® block-copolymers in medicine: from
chemical and biological versatility to rationalisation and clinical advances. Polymer Chemistry.
5(10): 3291-3297.
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Article