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Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells
Nigam, S. Burke, B.P. Davies, L.H. Domarkas, J. Wallis, J.F. Waddell, P.G. Waby, Jennifer S. Benoit, D.M. Seymour, A.-M. Cawthorne, C.
Nigam, S.
Burke, B.P.
Davies, L.H.
Domarkas, J.
Wallis, J.F.
Waddell, P.G.
Waby, Jennifer S.
Benoit, D.M.
Seymour, A.-M.
Cawthorne, C.
Publication Date
2016-05
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Rights
(c) 2016 The Authors. This is an Open Access article distributed under the Creative Commons CC-BY license (http://creativecommons.org/licenses/by/3.0/)
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Yes
Open Access status
openAccess
Accepted for publication
25/04/2016
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Abstract
The structural features required for mitochondrial uptake of BODIPY-based optical imaging agents have been explored. The first derivatives of this class of dyes shown to have mitochondrial membrane potential-dependent uptake in both cancer and heart cells have been developed.
Version
Published version
Citation
Nigam S, Burke BP, Davies LH et al (2016) Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells. Chemical Communications. 52(44): 7114-7117.
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Article