A Hydrocortisone Nanoparticle Dosage Form.
Zghebi, Salwa S. de Matas, Marcel Denyer, Morgan C.T. Blagden, Nicholas
Zghebi, Salwa S.
de Matas, Marcel
Denyer, Morgan C.T.
Blagden, Nicholas
Publication Date
09/03/2011
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Abstract
Of particular importance in recent years has been the development
of techniques for producing nanoparticles (NPs) of
poorly-water soluble drugs with dimensions less than 1000 nm
for which their high surface area can lead to improvements
in bioavailability. Furthermore, the small size of these particles
can also enable cellular uptake, particularly for positively charged systems. Therefore, an overall objective of this part
of the project was to produce nanoparticles with different
levels of positive surface charge using the bottom-up method.
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Zghebi, S., De Matas, M., Denyer, M. and Nicholas, B. (2010). A Hydrocortisone Nanoparticle Dosage Form. Journal of Pharmacy and Pharmacology. Vol. 62, No.10, Special Issue, pp. 1238-1239.
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