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Design, Synthesis and Preclinical Evaluation of MT1-MMP Targeted Methotrexate Prodrugs for the Treatment Of Osteosarcoma

Spencer, Hannah L.M.
Publication Date
2022
End of Embargo
Supervisor
Falconer, Robert A.
Loadman, Paul
Shnyder, Steven
Keywords
Osteosarcoma, Matrix metalloproteinases (MMPs), MT1-MMP, Metalloproteinase, Prodrug, Drug conjugate, Methotrexate
Rights
Creative Commons License
The University of Bradford theses are licenced under a Creative Commons Licence.
Peer-Reviewed
Open Access status
Accepted for publication
Institution
University of Bradford
Department
Institute of Cancer Therapeutics Faculty of Life Sciences
Awarded
2022
Embargo end date
2027-10-06
Collections
Theses
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Files
PhD Thesis
Adobe PDF, 7.92 MB
Additional title
Abstract
URI
http://hdl.handle.net/10454/19889
Version
Citation
Link to publisher’s version
Link to published version
Link to Version of Record
Type
Thesis
Qualification name
PhD
Notes
The full text will be available at the end of the embargo: 6th October 2027