Biocatalytic Amide Condensation and Gelation Controlled by Light
Sahoo, J.K. Nalluri, S.K.M. Javid, Nadeem Webb, H. Ulijn, R.V.
Sahoo, J.K.
Nalluri, S.K.M.
Javid, Nadeem
Webb, H.
Ulijn, R.V.
Publication Date
2014-03-25
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2014-03-25
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Abstract
We report on a supramolecular self-assembly system that displays coupled light switching, biocatalytic condensation/hydrolysis and gelation. The equilibrium state of this system can be regulated by light, favouring in situ formation, by protease catalysed peptide synthesis, of self-assembling trans-Azo-YF-NH2 in ambient light; however, irradiation with UV light gives rise to the cis-isomer, which readily hydrolyzes to its amino acid derivatives (cis-Azo-Y + F-NH2) with consequent gel dissolution.
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Sahoo JK, Nalluri SKM, Javid N et al (2014) Biocatalytic Amide Condensation and Gelation Controlled by Light. Chemical Communication. 50: 5462-5464.
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