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Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents
Lucas, S.J. Lord, Rianne M. Wilson, R.L. Phillips, Roger M. Sridharan, V. McGowan, P.C.
Lucas, S.J.
Lord, Rianne M.
Wilson, R.L.
Phillips, Roger M.
Sridharan, V.
McGowan, P.C.
Publication Date
2012-12-07
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Abstract
Several Ru-arene and Ir–Cp* complexes have been prepared
incorporating (N,N), (N,O) and (O,O) coordinating bidentate
ligands and have been found to be active against both HT-29
and MCF-7 cell lines. By incorporating a biologically active
ligand into a metal complex the anti-cancer activity is
increased.
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Lucas SJ, Lord RM, Wilson RL, Phillips RM, Sridharan V and McGowan PC (2012) Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents. Dalton Transactions. 41: 13800.
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