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Incremental and decremental L- and M-cone driven ERG responses: I. Square-wave pulse stimulation.
McKeefry, Declan J. Kremers, Jan Kommanapalli, Deepika Challa, Naveen K. Murray, I.J. Maguire, John Parry, Neil R.A.
McKeefry, Declan J.
Kremers, Jan
Kommanapalli, Deepika
Challa, Naveen K.
Murray, I.J.
Maguire, John
Parry, Neil R.A.
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2014-04
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Abstract
Electroretinograms (ERGs) elicited by transient, square-wave L- and M-cone isolating stimuli were recorded from human trichromatic (n=19) and dichromatic (n=4) observers. The stimuli were generated on a 4 primary LED stimulator and were equated in terms of cone modulation (cone contrast = 0.11) and retinal illuminance (12,000 trolands). L- and M-cone isolated ERGs had waveforms similar to those observed for luminance responses. However, M-cone ERGs exhibited a phase reversal in their responses to onset and offset stimuli relative to the L-cone responses. This on-off response reversal was observed in trichromats but not dichromats. Simultaneous counter-phase and in-phase combinations of L- and M-cone isolating stimuli generated responses that reflected chromatic and luminance processing, respectively. We conclude that L- and M-cone specific ERGs provide a measure of how photoreceptors contribute to post-receptoral mechanisms.
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McKeefry DJ, Kremers JJ, Kommanapalli D, Challa NK, Murray IJ, Maguire J and Parry NRA (2014) Incremental and decremental L- and M-cone-driven ERG responses: I. Square-wave pulse stimulation. Journal of the Optical Society of America A, 31(4): A159-169.
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