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Biomaterials for breast reconstruction: Promises, advances, and challenges

Abdul-Al, Mohamed
Zaernia, Amir
Sefat, Farshid
Publication Date
2020-11
End of Embargo
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Rights
© 2020 The Authors. Journal of Tissue Engineering and Regenerative Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Peer-Reviewed
Yes
Open Access status
Gold
Accepted for publication
2020-08-05
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Department
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Abstract
Breast reconstruction is the opportunity that provides the chance of having breast after undergoing surgical removal of the breast tissue due to cancer-related surgery. However, this varies on the stage of the cancer diagnosis and the procedure undertaken. There are many regenerative medicine methods that provide several initiatives and direct solutions to problems such as the development of “bioactive tissue,” which can regenerate adipose tissues with similar normal functions and structures. There have been several studies which have previously explored for the improvement of breast reconstruction including different variations of biomaterials, different fabrication and processing techniques, cells as well as growth factors which enable bioengineers and tissue engineers to reconstruct a suitable breast for patients with breast cancer. Many factors such as shape, proper volume, mechanical properties have been studies but very scattered with not adequate solutions for existing patients worldwide. This review article aims to cover recent advances in biomaterials, which can be used for reconstruction of breasts as well as looking at the various factors that might lead to individuals needing reconstruction and the materials that are available. The focus would be to look at the various biomaterials that are available to use for reconstruction, their properties, and their structural integrity.
Version
Published version
Citation
Abdul-Al M, Zaernia A and Sefat, F. (2020) Biomaterials for breast reconstruction: Promises, advances, and challenges. Journal of Tissue Engineering and Regenerative Medicine. 14(11): 1549–1569.
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Article
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